Multiple Protein Model Search
(Multiple Protein Model Search for NMR Drug Discovery)
This search engine has been developed for assisting NMR based drug discovery using modeled structures. The modeled structures are based on the entries archived in SAHG server which has been developed by Chie Motono Et al. (AIST). The SAHG project has comprehensively modeled structures for the sequences coded on human genome which are available from RefSeq database and using a lot of highly trustful homology search and modelling methods such as Modeller. Our server can search protein modeled structures by key words and the searched results will be linked with not only the original PDB entry but also the other life science databases such as BMRB, UniProt, OMIM and IntAct. Using the chemical shift data derived from BMRB will be useful for NMR based drug screening.
The search method is easy, so just type key words of protein in the entry and press search button. The search results will show ribbon model and the link of modeled structure archived in SAHG database and PDB like which has been used for homology modeling and sequence identity. If available, the links for BMRB, UniProt, OMIM and IntAct entries will appear.
Motono et. al. Nucleic Acids Res. 2011 Jan;39(Database issue):D487-93. doi: 10.1093/nar/gkq1057. Epub 2010 Nov 3.