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NS3(10-24)
Authors
Montserret, R., Penin, F.
Assembly
NS3
Entity
1. NS3 (polymer, Thiol state: all free), 15 monomers, 1560.862 Da Detail

TRGLLGCIIT SLTGR


Formula weight
1560.862 Da
Source organism
Hepacivirus C
Exptl. method
SOLUTION NMR
Data set
assigned_chemical_shifts, conformer_family_coord_set
Chem. Shift Complete
Sequence coverage: 100.0 %, Completeness: 84.9 %, Completeness (bb): 77.8 % Detail

Polymer type: polypeptide(L)

Total1H13C
All84.9 % (124 of 146)96.3 % (79 of 82)70.3 % (45 of 64)
Backbone77.8 % (56 of 72)100.0 % (30 of 30)61.9 % (26 of 42)
Sidechain91.9 % (79 of 86)94.2 % (49 of 52)88.2 % (30 of 34)
Methyl100.0 % (26 of 26)100.0 % (13 of 13)100.0 % (13 of 13)

1. NS3(10-24)

TRGLLGCIIT SLTGR

Sample

Solvent system SDS, Pressure 1 atm, Temperature 298 K, pH 6, Details NMR solution in Sodium Dodecyl Sulfate d25 (50mM final).


#NameIsotope labelingTypeConcentration
1NS3(10-24)natural abundance1.5 (±0.1) mM
2Sodium Dodecyl Sulfate[U-100% 2H]50 mM

Release date
2008-09-04
Citation
Structural determinants for membrane association and dynamic organization of the hepatitis C virus NS3-4A complex
Brass, V., Berke, J., Montserret, R., Blum, H.E., Penin, F., Moradpour, D.
Proc. Natl. Acad. Sci. U. S. A. (2008), 105, 14545-14550, PubMed 18799730 , DOI 10.1073/pnas.0807298105 ,
Entries sharing articles BMRB: 2 entries Detail
  BMRB: 20123 released on 2010-03-01
    Title NS4A(1-22)
  BMRB: 15580 released on 2008-09-04
    Title NS4A(1-21)
Related entities 1. NS3, : 1 : 74 : 3 : 1 : 19 entities Detail
Interaction partners 1. NS3, : 2 interactors Detail
Experiments performed 3 experiments Detail
Keywords NS3