BMRB: 17194

Oxki4a, spider derived antimicrobial peptide

Authors

Vassilevski, A.A., Dubovskii, P.V., Samsonova, O.V., Egorova, N.S., Kozlov, S.A., Feofanov, A.V., Arseniev, A.S., Grishin, E.V.

Assembly

Oxki4a

Entity

1. Oxki4a (polymer, Thiol state: all disulfide bound), 30 monomers, 3614.448 Da Detail

GIRCPKSWKC KAFKQRVLKR LLAMLRQHAF

Formula weight

3614.448 Da

Entity Connection

disulfide 1 Detail

---

ID	Type	Value order	Atom ID 1	Atom ID 2
1	disulfide	sing	1:CYS4:SG	1:CYS10:SG

Source organism

Oxyopes takobius

Exptl. method

solution NMR

Refine. method

torsion angle dynamics

Data set

assigned_chemical_shifts

Chem. Shift Complete

Sequence coverage: 100.0 %, Completeness: 95.3 %, Completeness (bb): 98.3 % Detail

Download

• NMR-STAR v3.1 (partial)
• BMRB/XML (partial)
• CSV
• TSV

Polymer type: polypeptide(L)

	Total	1H
All	95.3 % (204 of 214)	95.3 % (204 of 214)
Backbone	98.3 % (59 of 60)	98.3 % (59 of 60)
Sidechain	94.2 % (145 of 154)	94.2 % (145 of 154)
Aromatic	88.9 % (16 of 18)	88.9 % (16 of 18)
Methyl	100.0 % (15 of 15)	100.0 % (15 of 15)

1. entity

GIRCPKSWKC KAFKQRVLKR LLAMLRQHAF

Show sample condition

Sample #1

Solvent system 95% H2O/5% D2O, Pressure 1 atm, Temperature 273 K, pH 4.0 (±0.1), Details Oxki4a/dodecylphosphocholine-d38, H2O/D2O, pH 4.0, 30oC

#	Name	Isotope labeling	Type	Concentration
1	Oxki4a	natural abundance		1 (±0.1) mM
2	dodecylphosphocholine-d38	natural abundance		60 (±1.0) mM
3	D2O	natural abundance		5 %
4	H2O	natural abundance		95 %

Sample #2

Solvent system 100% D2O, Pressure 1 atm, Temperature 273 K, pH 4.0 (±0.1), Details Oxki4a/dodecylphosphocholine-d38(1:60), 100% D2O

#	Name	Isotope labeling	Type	Concentration
5	Oxki4a	natural abundance		1 mM
6	dodecylphosphocholine-d38	natural abundance		60 mM
7	D2O	natural abundance		100 %

Hide sample codition

Protein Blocks Logo

Calculated from 20 models in PDB: 2L3I, Strand ID: A Detail

---

Release date

2012-07-31

Citation

Novel lynx spider toxin shares common molecular architecture with defense peptides from frog skin
Dubovskii, P.V., Vassilevski, A.A., Samsonova, O.V., Egorova, N.S., Kozlov, S.A., Feofanov, A.V., Arseniev, A.S., Grishin, E.V.
FEBS J. (2011), 278, 4382-4393, PubMed 21933345 , DOI 10.1111/j.1742-4658.2011.08361.x , Abstract

Entries sharing articles Swiss-Prot: 1 entries Detail

Related entities 1. Oxki4a, : 1 : 1 : 6 entities Detail

Experiments performed 5 experiments Detail