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1H-NMR Assignment and Secondary structure of Human Insulin-Like Growth Factor-I (IGF-I) in Solution
Authors
Sato, A., Nishimura, S., Ohkubo, T., Kyogoku, Y., Koyama, S., Kobayashi, M., Yasuda, T., Kobayashi, Y.
Assembly
insulin-like growth factor-I
Entity
1. insulin-like growth factor-I (polymer), 70 monomers, 7654.677 Da Detail

GPETLCGAEL VDALQFVCGD RGFYFNKPTG YGSSSRRAPQ TGIVDECCFR SCDLRRLEMY CAPLKPAKSA


Formula weight
7654.677 Da
Source organism
Homo sapiens
Exptl. method
NMR
Data set
assigned_chemical_shifts
Chem. Shift Complete
Sequence coverage: 100.0 %, Completeness: 98.0 %, Completeness (bb): 97.9 % Detail

Polymer type: polypeptide(L)

Total1H
All98.0 % (399 of 407)98.0 % (399 of 407)
Backbone97.9 % (139 of 142)97.9 % (139 of 142)
Sidechain95.1 % (252 of 265)95.1 % (252 of 265)
Aromatic65.6 % (21 of 32)65.6 % (21 of 32)
Methyl100.0 % (29 of 29)100.0 % (29 of 29)

1. insulin-like growth factor-I

GPETLCGAEL VDALQFVCGD RGFYFNKPTG YGSSSRRAPQ TGIVDECCFR SCDLRRLEMY CAPLKPAKSA

Sample

Temperature 313 K, pH 3



Release date
1995-07-30
Citation
1H-NMR assignment and secondary structure of human insulin-like growth factor-I (IGF-I) in solution
Sato, A., Nishimura, S., Ohkubo, T., Kyogoku, Y., Koyama, S., Kobayashi, M., Yasuda, T., Kobayashi, Y.
J. Biochem. (1992), 111, 529-536, PubMed 1319992 , DOI 10.1093/oxfordjournals.jbchem.a123791 ,
Related entities 1. insulin-like growth factor-I, : 1 : 30 : 3 : 6 : 155 entities Detail
Interaction partners 1. insulin-like growth factor-I, : 9 interactors Detail
Experiments performed 1 experiments Detail
Chemical shift validation 3 contents Detail