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Sequential assignment of proton resonances in the NMR spectrum of Zn-substituted alpha chains from human hemoglobin
Authors
Martineau, L., Craescu, C.T.
Assembly
hemoglobin A alpha chain
Entity
1. hemoglobin A alpha chain (polymer), 141 monomers, 15126.15 Da Detail

VLSPADKTNV KAAWGKVGAH AGEYGAEALE RMFLSFPTTK TYFPHFDLSH GSAQVKGHGK KVADALTNAV AHVDDMPNAL SALSDLHAHK LRVDPVNFKL LSHCLLVTLA AHLPAEFTPA VHASLDKFLA SVSTVLTSKY R


Formula weight
15126.15 Da
Source organism
Homo sapiens
Exptl. method
NMR
Data set
assigned_chemical_shifts
Chem. Shift Complete
Sequence coverage: 75.9 %, Completeness: 64.9 %, Completeness (bb): 70.9 % Detail

Polymer type: polypeptide(L)

Total1H
All64.9 % (522 of 804)64.9 % (522 of 804)
Backbone70.9 % (195 of 275)70.9 % (195 of 275)
Sidechain61.8 % (327 of 529)61.8 % (327 of 529)
Aromatic83.6 % (61 of 73)83.6 % (61 of 73)
Methyl79.3 % (73 of 92)79.3 % (73 of 92)

1. hemoglobin A alpha chain

VLSPADKTNV KAAWGKVGAH AGEYGAEALE RMFLSFPTTK TYFPHFDLSH GSAQVKGHGK KVADALTNAV AHVDDMPNAL SALSDLHAHK LRVDPVNFKL LSHCLLVTLA AHLPAEFTPA VHASLDKFLA SVSTVLTSKY R

Sample

Temperature 310 K, pH 5.6



Release date
1995-07-30
Citation
Sequential assignment of proton resonances in the NMR spectrum of Zn-substituted alpha chains from human hemoglobin. Ligand-induced tertiary changes in the heme pocket
Martineau, L., Craescu, C.T.
Eur. J. Biochem. (1993), 214, 383-393, PubMed 8513788 , DOI 10.1111/j.1432-1033.1993.tb17934.x ,
Related entities 1. hemoglobin A alpha chain, : 1 : 100 : 1 : 6 : 100 entities Detail
Interaction partners 1. hemoglobin A alpha chain, : 30 interactors Detail
Experiments performed 1 experiments Detail