BMRB: 4630

NMR STRUCTURE OF THROMBOMODULIN EGF(4-5)

Authors

Wood, M.J., Sampoli-Benitez, B.A., Komives, E.A.

Assembly

THROMBOMODULIN

Entity

1. THROMBOMODULIN (polymer, Thiol state: all disulfide bound), 83 monomers, 9295.306 Da Detail

HMEPVDPCFR ANCEYQCQPL NQTSYLCVCA EGFAPIPHEP HRCQMFCNQT ACPADCDPNT QASCECPEGY ILDDGFICTD IDE

2. NAG (non-polymer), 221.208 × 2 Da

Total weight

9737.722 Da

Max. entity weight

9295.306 Da

Entity Connection

disulfide 6, covalent 2 Detail

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ID	Type	Value order	Atom ID 1	Atom ID 2
1	disulfide	sing	1:CYS8:SG	1:CYS17:SG
2	disulfide	sing	1:CYS13:SG	1:CYS27:SG
3	disulfide	sing	1:CYS29:SG	1:CYS43:SG
4	disulfide	sing	1:CYS47:SG	1:CYS52:SG
5	disulfide	sing	1:CYS56:SG	1:CYS64:SG
6	disulfide	sing	1:CYS66:SG	1:CYS78:SG
7	covalent	sing	1:ASN21:ND2	2:NAG1:C1
8	covalent	sing	1:ASN48:ND2	2:NAG1:C1

Source organism

Homo sapiens

Exptl. method

NMR

Refine. method

distance geometry simulated annealing refinment

Data set

coupling_constants

Protein Blocks Logo

Calculated from 12 models in PDB: 1DQB, Strand ID: A Detail

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Coupling constant

43 J values in 2 lists
Field strength (¹H) 600 MHz, Pressure 1 atm, Temperature 310 K, pH 6.5 Detail

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Pressure 1 atm, Temperature 310 K, pH 6.5

List #1 JHNHA, Field strength (¹H) 600 MHz

List #2 JHAHB, Field strength (¹H) 600 MHz

Release date

2001-05-06

Citation

Solution structure of the smallest cofactor-active fragment of thrombomodulin
Wood, M.J., Sampoli-Benitez, B.A., Komives, E.A.
Nat. Struct. Biol. (2000), 7, 200-204, PubMed 10700277 , DOI 10.1038/73302 , Abstract

Related entities 1. THROMBOMODULIN, : 1 : 63 entities Detail

Interaction partners 1. THROMBOMODULIN, : 4 interactors Detail

Experiments performed 3 experiments Detail