Role of backbone dynamics and structure in controlling the hydrolysis constants of serine proteinase inhibitors
ID | Type | Value order | Atom ID 1 | Atom ID 2 |
---|---|---|---|---|
1 | disulfide | sing | 1:CYS8:SG | 1:CYS38:SG |
2 | disulfide | sing | 1:CYS16:SG | 1:CYS35:SG |
3 | disulfide | sing | 1:CYS24:SG | 1:CYS56:SG |
Polymer type: polypeptide(L)
Total | 1H | 13C | 15N | |
---|---|---|---|---|
All | 25.5 % (155 of 609) | 16.6 % (52 of 313) | 21.4 % (51 of 238) | 89.7 % (52 of 58) |
Backbone | 47.0 % (155 of 330) | 46.0 % (52 of 113) | 31.1 % (51 of 164) | 98.1 % (52 of 53) |
Sidechain | 0.0 % (0 of 331) | 0.0 % (0 of 200) | 0.0 % (0 of 126) | 0.0 % (0 of 5) |
Aromatic | 0.0 % (0 of 48) | 0.0 % (0 of 24) | 0.0 % (0 of 24) | |
Methyl | 0.0 % (0 of 52) | 0.0 % (0 of 26) | 0.0 % (0 of 26) |
1. Ovomucoid Third Domain from Turkey
LAAVSVDCSE YPKPACTLEY RPLCGSDNKT YGNKCNFCNA VVESNGTLTL SHFGKCTemperature 298 (±1) K, pH 6.0 (±0.2)
# | Name | Isotope labeling | Type | Concentration |
---|---|---|---|---|
1 | Ovomucoid Third Domain from Turkey | [U-13C; U-15N] | 2 mM |