BMRB: 6064

E6-binding zinc finger (E6apc1)

Authors

Liu, Y., Liu, Z., Androphy, E., Chen, J., Baleja, J.D.

Assembly

E6apc1 peptide

Entity

1. E6apc1 peptide (polymer, Thiol state: not reported), 31 monomers, 3580.233 Da Detail

XYKFACPECP KRFMRSDHLT LHILLHENKK X

Formula weight

3580.233 Da

Source organism

Papillomaviridae

Exptl. method

NMR

Refine. method

dynamical annealing

Data set

assigned_chemical_shifts

Chem. Shift Complete

Sequence coverage: 90.3 %, Completeness: 71.4 %, Completeness (bb): 96.4 % Detail

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Polymer type: polypeptide(L)

	Total	1H
All	71.4 % (142 of 199)	71.4 % (142 of 199)
Backbone	96.4 % (54 of 56)	96.4 % (54 of 56)
Sidechain	61.5 % (88 of 143)	61.5 % (88 of 143)
Aromatic	65.0 % (13 of 20)	65.0 % (13 of 20)
Methyl	100.0 % (12 of 12)	100.0 % (12 of 12)

1. E6apc1

XYKFACPECP KRFMRSDHLT LHILLHENKK X

Show sample condition

Sample

Pressure 1 atm, Temperature 298 K, pH 6.0

#	Name	Isotope labeling	Type	Concentration
1	E6apc1			1.2 ~ 3.0 mM
2	imidazole	[U-2H]		10 mM
3	ZnSO4			4 mM
4	DTT			1 mM
5	H2O			90 %
6	D2O			10 %

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Calculated from 50 models in PDB: 1RIK, Strand ID: A Detail

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Release date

2008-07-16

Citation

Design and characterization of helical peptides that inhibit the E6 protein of papillomavirus
Liu, Y., Liu, Z., Androphy, E., Chen, J., Baleja, J.D.
Biochemistry (2004), 43, 7421-7431, PubMed 15182185 , DOI 10.1021/bi049552a , Abstract

Related entities 1. E6apc1 peptide, : 1 : 520 entities Detail

Experiments performed 3 experiments Detail