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High Resolution Nuclear Magnetic Resonance Studies of the Active Site of Chymotrypsin II. Polarization of Histidine 57 by Substrate Analogues and Competitive Inhibitors
Authors
Robillard, G., Shulman, R.G.
Assembly
chymotrypsin
Entity
1. chymotrypsin (polymer), 230 monomers, 24185.10 Da Detail

IVNGEEAVPG SWPWQVSLQD KTGFHFCGGS LINENWVVTA AHCGVTTSDV VVAGEFDQGS SSEKIQKLKI AKVFKNSKYN SLTINNDITL LKLSTAASFS QTVSAVCLPS ASDDFAAGTT CVVTGWGLTR YTNANTPDRL QQASLPLLSN TNCKKYWGTK IKDAMICAGA SGVSSCMGDS GGPLVCKKNG AWTLVGIVSW GSSTCSTSTP GVYARVTALV NWVQQTLAAN


Formula weight
24185.1 Da
Source organism
Bos taurus
Exptl. method
NMR
Data set
assigned_chemical_shifts
Chem. Shift Complete
Sequence coverage: 0.0 %, Completeness: 0.0 %, Completeness (bb): 0.0 % Detail

Polymer type: polypeptide(L)

Total1H
All 0.0 % (0 of 1276) 0.0 % (0 of 1276)
Backbone 0.0 % (0 of 453) 0.0 % (0 of 453)
Sidechain 0.0 % (0 of 823) 0.0 % (0 of 823)
Aromatic 0.0 % (0 of 98) 0.0 % (0 of 98)
Methyl 0.0 % (0 of 139) 0.0 % (0 of 139)

1. chymotrypsin

IVNGEEAVPG SWPWQVSLQD KTGFHFCGGS LINENWVVTA AHCGVTTSDV VVAGEFDQGS SSEKIQKLKI AKVFKNSKYN SLTINNDITL LKLSTAASFS QTVSAVCLPS ASDDFAAGTT CVVTGWGLTR YTNANTPDRL QQASLPLLSN TNCKKYWGTK IKDAMICAGA SGVSSCMGDS GGPLVCKKNG AWTLVGIVSW GSSTCSTSTP GVYARVTALV NWVQQTLAAN

Sample

Temperature 277 K, pH 9.5



Release date
1995-07-30
Citation
High resolution nuclear magnetic resonance studies of the active site of chymotrypsin. II. Polarization of histidine 57 by substrate analogues and competitive inhibitors
Robillard, G., Shulman, R.G.
J. Mol. Biol. (1974), 86, 541-558, PubMed 4852270 , DOI 10.1016/0022-2836(74)90179-x ,
Related entities 1. chymotrypsin, : 1 : 26 : 105 entities Detail
Interaction partners 1. chymotrypsin, : 6 interactors Detail
Experiments performed 1 experiments Detail