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Sequence-specific 1H-NMR assignments for the aromatic region of several biologically active, monomeric insulins including native human insulin
Authors
Roy, M., Lee, R.W.-K., Kaarsholm, N.C., Thogersen, H., Brange, J., Dunn, M.F.
Assembly
insulin A chain
Entity
1. insulin A chain (polymer), 21 monomers, 2383.696 Da Detail

GIVEQCCTSI CSLYQLENYC N


Formula weight
2383.696 Da
Source organism
Homo sapiens
Exptl. method
NMR
Data set
assigned_chemical_shifts
Chem. Shift Complete
Sequence coverage: 19.0 %, Completeness: 13.3 %, Completeness (bb): 7.1 % Detail

Polymer type: polypeptide(L)

Total1H
All13.3 % (16 of 120)13.3 % (16 of 120)
Backbone 7.1 % (3 of 42) 7.1 % (3 of 42)
Sidechain16.7 % (13 of 78)16.7 % (13 of 78)
Aromatic100.0 % (8 of 8)100.0 % (8 of 8)
Methyl18.2 % (2 of 11)18.2 % (2 of 11)

1. insulin A chain

GIVEQCCTSI CSLYQLENYC N

Sample

Temperature 298 K, pH 8.5



Release date
1995-07-30
Citation
Sequence-specific 1H-NMR assignments for the aromatic region of several biologically active, monomeric insulins including native human insulin
Roy, M., Lee, R.W.-K., Kaarsholm, N.C., Thogersen, H., Brange, J., Dunn, M.F.
Biochim. Biophys. Acta (1990), 1053, 63-73, PubMed 2194578 , DOI 10.1016/0167-4889(90)90027-b ,
Related entities 1. insulin A chain, : 1 : 110 : 9 : 7 : 74 entities Detail
Interaction partners 1. insulin A chain, : 2 interactors Detail
Experiments performed 1 experiments Detail